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Index > Protein center > ITGB2(Gene name) > Bovine
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  • ITGB2 (Gene name),
  • Integrin beta-2 (Protein name ),  ITB2_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ITGB2(CD18);
    Protein name:
    Integrin beta-2;
    Alternative:
    Complement receptor C3 subunit beta;Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;
    CD:
    CD18;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Heterodimer of an alpha and a beta subunit. Beta-2 associates with either alpha-L, alpha-M, alpha-X or alpha-D. Interacts with COPS5 and RANBP9. Interacts with FGR.
    Function:
    Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    769
    Sequence:
    50:
    MLRQRPQLLL | LAGLLALQSV | LSQECTNYKV | STCRDCIESG | PGCAWCQKLN | 
    100:
    FTGQGEPDSI | RCDTRAELLS | KGCPADDIME | PKSLAETRDS | QAGSRKQLSP | 
    150:
    QEVTLYLRPG | QAVAFNVTFR | RAKGYPIDLY | YLMDLSYSMV | DDLVNVKKLG | 
    200:
    GDLLRALNGI | TESGRIGFGS | FVDKTVLPFV | NTHPEKLRNP | CPNKEKECQP | 
    250:
    PFAFRHVLKL | TDNSKQFETE | VGKQLISGNL | DAPEGGLDAM | MQVAACPEEI | 
    300:
    GWRNVTRLLV | FATDDGFHFA | GDGKLGAILT | PNDGRCHLED | NLYKSSNEFD | 
    350:
    YPSVGQLAHK | LAESNIQPIF | AVTKKMVKTY | EKLTEIIPKS | AVGELSEDSR | 
    400:
    NVVELIKNAY | NKLSSRVFLD | HSTLPDTLKV | TYDSFCSNGK | SQVDQPRGDC | 
    450:
    DGVQINVPIT | FQVKVTATEC | IQQQSFTIRA | LGFTDTVTVR | VLPQCECQCR | 
    500:
    DASRDGSICG | GRGSMECGVC | RCDAGYIGKN | CECQTQGRSS | QELEGSCRKD | 
    550:
    NSSIICSGLG | DCICGQCVCH | TSDVPNKKIY | GQFCECDNVN | CERYDGQVCG | 
    600:
    GEKRGLCFCG | TCRCDEQYEG | SACQCLKSTQ | GCLNLDGVEC | SGRGRCRCNV | 
    650:
    CQCDPGYQPP | LCSECPGCPV | PCAGFAPCTE | CLKFDKGPFA | KNCSAACGQT | 
    700:
    KLLSSPVPGR | KCKERDSEGC | WMTYTLVQRD | GRDRYDVHVD | DMLECVKGPN | 
    750:
    IAAIVGGTVG | GVVLVGILLL | VIWKALTHLS | DLREYHRFEK | EKLKSQWNND | 
    769:
    NPLFKSATTT | VMNPKFAES
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    String:
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Integrin beta-2
    Cat.:
    E0236h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Integrin beta-2
    Cat.:
    E0236p
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    ELISA Kit for Bovine Integrin beta-2
    Cat.:
    E0236b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Bovine Integrin beta-2
    Cat.:
    E0236m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Integrin beta-2
    Cat.:
    U0236b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Integrin beta-2
    Cat.:
    U0236m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Integrin beta-2
    Cat.:
    U0236p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Integrin beta-2
    Cat.:
    U0236h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Integrin beta-2
    Polyclonal Antibody for Bovine Integrin beta-2
    Cat.:
    P0236Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Integrin beta-2
    Cat.:
    P0236Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Integrin beta-2
    Monoclonal Antibody for Bovine Integrin beta-2
    Monoclonal Antibody for Bovine Integrin beta-2
    Monoclonal Antibody for Bovine Integrin beta-2
    Monoclonal Antibody for Bovine Integrin beta-2
    Protein for Bovine Integrin beta-2
    Protein for Bovine Integrin beta-2
    Protein for Bovine Integrin beta-2
    Protein for Bovine Integrin beta-2

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    References
    1. 1.
      "Sequence of the bovine CD18-encoding cDNA: comparison with the human and murine glycoproteins."
      Shuster D.E. , Bosworth B.T. , Kehrli M.E. Jr.
      Gene114:267-271(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Identification and prevalence of a genetic defect that causes leukocyte adhesion deficiency in Holstein cattle."
      Shuster D.E. , Kehrli M.E. Jr. , Ackermann M.R. , Gilbert R.O.
      Proc. Natl. Acad. Sci. U.S.A.89:9225-9229(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LAD GLY-128
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